{"acc":"B5XZ37","reviewed":true,"gene":"hslU","proteome":"UP000001734","name":"ATP-dependent protease ATPase subunit HslU","length":444,"organism":"Klebsiella pneumoniae (strain 342)","ncbi_taxon_id":507522,"taxonomy":["Bacteria","Pseudomonadota","Gammaproteobacteria","Enterobacterales","Enterobacteriaceae","Klebsiella/Raoultella group","Klebsiella"],"sequence":"MSEMTPREIVSELDKHIIGQDAAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAIKMVRMQSIDKNRYRAEELAEERVLDVLIPPAKNNWGQAEQPQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMSPPGMEEMTSQLQSMFQNLGGQKQKPRKLKIKDAMKLLIEEEAAKLVNPEELKQEAIDAVEQHGIVFIDEIDKICKRGGNSSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVASPSDLIPELQGRLPIRVELKALTTHDFERILTEPNASITVQYKALMATEGVNIEFTEDGIKRIAQAAWQVNETTENIGARRLHTVLERLVEDISYDASEMNGQTVIIDAEYVSKHLDVLVADEDLSRFIL","localization":["Cytoplasm"],"uniref100":"UniRef100_B5XZ37","uniref90":"UniRef90_B5F0S2","uniref50":"UniRef50_P0A6H6","uniparc":"UPI0001813A14","homology-domain-gene3d":{"regions":[[193,334],[3,114]],"content_fraction":0.572,"content_count":254,"regions_ids":["3.40.50.300","3.40.50.300"],"regions_names":["P-loop containing nucleoside triphosphate hydrolase","P-loop containing nucleoside triphosphate hydrolase"]},"homology-domain-merge":{"regions":[[3,136],[187,334]],"content_fraction":0.635,"content_count":282},"homology-domain-pfam":{"regions":[[187,330],[53,136]],"content_fraction":0.514,"content_count":228,"regions_ids":["PF07724","PF00004"],"regions_names":["ATPase, AAA-type, core","ATPase, AAA-type, core"]},"level":1,"prediction-disorder-alphafold":{"scores":[0.369,0.385,0.39,0.379,0.372,0.374,0.361,0.331,0.345,0.353,0.341,0.311,0.329,0.317,0.307,0.276,0.278,0.266,0.256,0.227,0.218,0.22,0.223,0.22,0.21,0.223,0.232,0.23,0.243,0.264,0.295,0.309,0.313,0.314,0.323,0.338,0.353,0.331,0.341,0.343,0.343,0.328,0.327,0.333,0.33,0.331,0.346,0.342,0.326,0.335,0.324,0.307,0.304,0.281,0.258,0.244,0.233,0.225,0.198,0.198,0.193,0.182,0.198,0.184,0.184,0.191,0.198,0.21,0.205,0.22,0.208,0.204,0.211,0.214,0.215,0.242,0.273,0.285,0.325,0.361,0.36,0.372,0.396,0.399,0.382,0.377,0.372,0.349,0.358,0.37,0.363,0.355,0.356,0.366,0.348,0.354,0.371,0.364,0.359,0.371,0.363,0.332,0.313,0.285,0.272,0.282,0.272,0.27,0.301,0.306,0.302,0.313,0.33,0.331,0.318,0.323,0.331,0.326,0.313,0.313,0.322,0.31,0.315,0.324,0.33,0.319,0.336,0.362,0.36,0.377,0.39,0.4,0.404,0.391,0.394,0.431,0.447,0.47,0.491,0.507,0.521,0.544,0.554,0.561,0.583,0.587,0.584,0.579,0.595,0.585,0.575,0.576,0.566,0.572,0.555,0.521,0.51,0.513,0.518,0.519,0.484,0.483,0.445,0.432,0.419,0.42,0.398,0.408,0.419,0.435,0.441,0.458,0.487,0.478,0.5,0.509,0.508,0.521,0.539,0.533,0.554,0.565,0.553,0.532,0.526,0.541,0.533,0.543,0.539,0.557,0.566,0.573,0.577,0.596,0.58,0.572,0.572,0.565,0.567,0.55,0.56,0.559,0.552,0.529,0.528,0.502,0.502,0.503,0.498,0.485,0.493,0.493,0.48,0.472,0.48,0.457,0.443,0.411,0.394,0.393,0.392,0.367,0.354,0.36,0.361,0.366,0.347,0.333,0.343,0.343,0.343,0.324,0.323,0.328,0.322,0.304,0.297,0.307,0.299,0.272,0.266,0.262,0.264,0.249,0.241,0.226,0.221,0.217,0.192,0.169,0.158,0.175,0.197,0.212,0.231,0.269,0.289,0.297,0.315,0.318,0.343,0.346,0.343,0.349,0.359,0.36,0.36,0.385,0.405,0.392,0.397,0.413,0.4,0.405,0.421,0.418,0.406,0.392,0.357,0.344,0.311,0.307,0.291,0.281,0.301,0.269,0.279,0.273,0.285,0.278,0.278,0.278,0.252,0.229,0.229,0.223,0.206,0.214,0.214,0.228,0.243,0.238,0.229,0.236,0.237,0.248,0.229,0.222,0.238,0.236,0.237,0.223,0.251,0.246,0.243,0.264,0.271,0.292,0.294,0.324,0.324,0.355,0.371,0.371,0.358,0.344,0.362,0.357,0.35,0.335,0.332,0.339,0.336,0.327,0.326,0.329,0.343,0.339,0.328,0.33,0.311,0.324,0.322,0.324,0.311,0.334,0.326,0.305,0.322,0.333,0.336,0.328,0.322,0.337,0.327,0.333,0.332,0.342,0.36,0.36,0.356,0.337,0.332,0.339,0.336,0.333,0.327,0.309,0.304,0.305,0.3,0.277,0.276,0.277,0.259,0.25,0.267,0.285,0.281,0.283,0.272,0.288,0.279,0.242,0.244,0.259,0.256,0.235,0.249,0.263,0.263,0.249,0.267,0.286,0.269,0.268,0.302,0.318,0.295,0.31,0.336,0.313,0.326,0.346,0.364,0.379,0.361,0.382,0.381,0.373,0.367,0.399,0.407,0.385,0.381,0.413,0.421,0.402,0.397,0.426,0.413,0.381,0.395,0.41,0.404,0.395,0.404,0.373,0.366,0.383,0.377,0.377,0.372,0.409,0.42,0.41,0.395,0.413,0.433,0.439,0.439,0.433,0.436,0.454],"content_fraction":0.014,"content_count":6},"prediction-disorder-dis465":{"regions":[[1,9],[143,159],[205,215],[266,275],[442,444]],"content_count":50,"content_fraction":0.113},"prediction-disorder-disHL":{"regions":[[1,5],[7,8],[13,25],[41,58],[74,98],[113,121],[141,152],[164,174],[178,181],[206,214],[230,238],[265,283],[292,294],[337,352],[385,396],[409,415],[432,438],[440,444]],"content_count":186,"content_fraction":0.419},"prediction-disorder-espN":{"regions":[[1,8],[137,155],[180,214],[264,278]],"content_count":77,"content_fraction":0.173},"prediction-disorder-espX":{"regions":[[1,9],[144,166],[266,270]],"content_count":37,"content_fraction":0.083},"prediction-disorder-glo":{"regions":[[1,1],[4,5],[55,58],[141,146],[187,190],[262,275],[435,435],[437,437],[439,439]],"content_count":34,"content_fraction":0.077},"prediction-disorder-iupl":{"regions":[[1,1],[5,5],[138,161],[179,180],[184,206],[210,211],[237,240],[265,277]],"content_count":70,"content_fraction":0.158},"prediction-disorder-iups":{"regions":[[1,8],[142,167],[172,172],[174,174],[176,176],[184,208],[210,211],[214,214],[266,267],[269,276],[444,444]],"content_count":76,"content_fraction":0.171},"prediction-disorder-th_50":{"regions":[[1,8],[141,159],[187,190],[205,208],[210,211],[214,214],[265,276]],"content_count":50,"content_fraction":0.113},"prediction-lip-alphafold":{"scores":[0.369,0.385,0.39,0.379,0.372,0.374,0.361,0.331,0.345,0.353,0.341,0.311,0.329,0.317,0.307,0.276,0.278,0.266,0.256,0.227,0.218,0.22,0.223,0.22,0.21,0.223,0.232,0.23,0.243,0.264,0.295,0.309,0.313,0.314,0.323,0.338,0.353,0.331,0.341,0.343,0.343,0.328,0.327,0.333,0.33,0.331,0.346,0.342,0.326,0.335,0.324,0.307,0.304,0.281,0.258,0.244,0.233,0.225,0.198,0.198,0.193,0.182,0.198,0.184,0.184,0.191,0.198,0.21,0.205,0.22,0.208,0.204,0.211,0.214,0.215,0.242,0.273,0.285,0.325,0.361,0.36,0.372,0.396,0.399,0.382,0.377,0.372,0.349,0.358,0.37,0.363,0.355,0.356,0.366,0.348,0.354,0.371,0.364,0.359,0.371,0.363,0.332,0.313,0.285,0.272,0.282,0.272,0.27,0.301,0.306,0.302,0.313,0.33,0.331,0.318,0.323,0.331,0.326,0.313,0.313,0.322,0.31,0.315,0.324,0.33,0.319,0.336,0.362,0.36,0.377,0.39,0.4,0.404,0.391,0.394,0.431,0.447,0.47,0.491,0.507,0.521,0.544,0.554,0.561,0.836,0.838,0.818,0.579,0.814,0.815,0.575,0.576,0.566,0.572,0.555,0.521,0.51,0.513,0.518,0.519,0.484,0.483,0.445,0.432,0.419,0.42,0.398,0.408,0.419,0.435,0.441,0.458,0.487,0.478,0.5,0.509,0.508,0.521,0.539,0.533,0.554,0.565,0.553,0.532,0.526,0.541,0.533,0.543,0.539,0.557,0.566,0.573,0.577,0.902,0.58,0.572,0.572,0.565,0.567,0.55,0.56,0.559,0.552,0.529,0.528,0.502,0.502,0.503,0.498,0.485,0.493,0.493,0.48,0.472,0.48,0.457,0.443,0.411,0.394,0.393,0.392,0.367,0.354,0.36,0.361,0.366,0.347,0.333,0.343,0.343,0.343,0.324,0.323,0.328,0.322,0.304,0.297,0.307,0.299,0.272,0.266,0.262,0.264,0.249,0.241,0.226,0.221,0.217,0.192,0.169,0.158,0.175,0.197,0.212,0.231,0.269,0.289,0.297,0.315,0.318,0.343,0.346,0.343,0.349,0.359,0.36,0.36,0.385,0.405,0.392,0.397,0.413,0.4,0.405,0.421,0.418,0.406,0.392,0.357,0.344,0.311,0.307,0.291,0.281,0.301,0.269,0.279,0.273,0.285,0.278,0.278,0.278,0.252,0.229,0.229,0.223,0.206,0.214,0.214,0.228,0.243,0.238,0.229,0.236,0.237,0.248,0.229,0.222,0.238,0.236,0.237,0.223,0.251,0.246,0.243,0.264,0.271,0.292,0.294,0.324,0.324,0.355,0.371,0.371,0.358,0.344,0.362,0.357,0.35,0.335,0.332,0.339,0.336,0.327,0.326,0.329,0.343,0.339,0.328,0.33,0.311,0.324,0.322,0.324,0.311,0.334,0.326,0.305,0.322,0.333,0.336,0.328,0.322,0.337,0.327,0.333,0.332,0.342,0.36,0.36,0.356,0.337,0.332,0.339,0.336,0.333,0.327,0.309,0.304,0.305,0.3,0.277,0.276,0.277,0.259,0.25,0.267,0.285,0.281,0.283,0.272,0.288,0.279,0.242,0.244,0.259,0.256,0.235,0.249,0.263,0.263,0.249,0.267,0.286,0.269,0.268,0.302,0.318,0.295,0.31,0.336,0.313,0.326,0.346,0.364,0.379,0.361,0.382,0.381,0.373,0.367,0.399,0.407,0.385,0.381,0.413,0.421,0.402,0.397,0.426,0.413,0.381,0.395,0.41,0.404,0.395,0.404,0.373,0.366,0.383,0.377,0.377,0.372,0.409,0.42,0.41,0.395,0.413,0.433,0.439,0.439,0.433,0.436,0.454],"content_fraction":0.014,"content_count":6},"prediction-lip-anchor":{"regions":[[134,136],[173,186],[199,204],[219,226],[252,259],[304,307]],"content_count":43,"content_fraction":0.097},"prediction-lip-priority":{"regions":[[134,136],[173,186],[199,204],[219,226],[252,259],[304,307]],"content_fraction":0.097,"content_count":43},"prediction-plddt-alphafold":{"scores":[0.609,0.727,0.876,0.919,0.949,0.954,0.965,0.965,0.958,0.971,0.966,0.956,0.965,0.968,0.964,0.96,0.963,0.969,0.951,0.962,0.962,0.96,0.966,0.973,0.968,0.957,0.955,0.958,0.943,0.929,0.926,0.935,0.925,0.89,0.911,0.94,0.923,0.875,0.912,0.938,0.946,0.891,0.916,0.929,0.906,0.876,0.907,0.922,0.917,0.929,0.939,0.969,0.975,0.98,0.98,0.974,0.95,0.933,0.924,0.933,0.96,0.952,0.965,0.959,0.961,0.971,0.966,0.965,0.96,0.95,0.954,0.943,0.933,0.921,0.929,0.948,0.974,0.98,0.979,0.976,0.964,0.947,0.932,0.894,0.89,0.874,0.785,0.64,0.522,0.456,0.42,0.497,0.531,0.636,0.845,0.911,0.927,0.935,0.963,0.976,0.96,0.965,0.979,0.979,0.965,0.969,0.974,0.955,0.942,0.944,0.939,0.918,0.905,0.909,0.895,0.874,0.875,0.888,0.892,0.882,0.907,0.909,0.912,0.921,0.913,0.919,0.919,0.917,0.899,0.885,0.905,0.891,0.878,0.87,0.85,0.856,0.797,0.764,0.713,0.713,0.687,0.621,0.677,0.633,0.609,0.613,0.567,0.58,0.555,0.557,0.617,0.677,0.778,0.83,0.823,0.858,0.873,0.885,0.886,0.903,0.908,0.893,0.896,0.894,0.907,0.864,0.875,0.867,0.871,0.893,0.877,0.901,0.882,0.894,0.861,0.843,0.808,0.762,0.686,0.641,0.583,0.584,0.604,0.675,0.684,0.722,0.762,0.755,0.792,0.804,0.774,0.804,0.813,0.766,0.799,0.828,0.804,0.814,0.82,0.802,0.78,0.79,0.767,0.749,0.733,0.752,0.67,0.614,0.621,0.676,0.76,0.795,0.848,0.853,0.892,0.909,0.928,0.909,0.909,0.912,0.914,0.904,0.897,0.89,0.904,0.896,0.851,0.866,0.888,0.863,0.822,0.867,0.873,0.854,0.897,0.884,0.903,0.918,0.928,0.94,0.947,0.949,0.967,0.972,0.955,0.958,0.976,0.963,0.928,0.937,0.968,0.977,0.983,0.984,0.976,0.968,0.951,0.954,0.946,0.924,0.915,0.905,0.831,0.705,0.612,0.585,0.561,0.581,0.608,0.645,0.694,0.653,0.723,0.802,0.845,0.869,0.886,0.909,0.931,0.92,0.927,0.949,0.947,0.951,0.965,0.953,0.938,0.948,0.961,0.975,0.967,0.957,0.95,0.931,0.932,0.937,0.967,0.98,0.976,0.976,0.96,0.954,0.971,0.97,0.979,0.981,0.98,0.97,0.959,0.943,0.937,0.89,0.875,0.904,0.927,0.936,0.932,0.932,0.944,0.935,0.941,0.942,0.948,0.944,0.939,0.949,0.958,0.941,0.95,0.96,0.97,0.965,0.97,0.95,0.946,0.953,0.958,0.958,0.967,0.968,0.975,0.973,0.976,0.974,0.971,0.955,0.961,0.968,0.939,0.939,0.953,0.944,0.958,0.959,0.958,0.948,0.954,0.961,0.958,0.951,0.953,0.959,0.944,0.943,0.957,0.957,0.95,0.958,0.963,0.97,0.961,0.965,0.962,0.972,0.972,0.959,0.967,0.97,0.962,0.95,0.96,0.955,0.943,0.939,0.937,0.925,0.905,0.905,0.891,0.909,0.926,0.939,0.956,0.948,0.954,0.964,0.938,0.941,0.951,0.944,0.939,0.937,0.945,0.935,0.94,0.925,0.928,0.939,0.955,0.944,0.933,0.927,0.933,0.891,0.909,0.915,0.938,0.948,0.942,0.961,0.956,0.959,0.96,0.956,0.952,0.954,0.939,0.939,0.915,0.927,0.894,0.881,0.886,0.886,0.884,0.895,0.872,0.873,0.863,0.84,0.855,0.875,0.858,0.839],"content_fraction":0.912,"content_count":405,"regions":[[2,87],[95,140],[153,178],[186,206],[211,264],[273,444]]}}