{"acc":"A0A8C8XRM6","gene":"SLC4A10","proteome":"UP000694399","name":"Anion exchange protein","length":1118,"organism":"Panthera leo (Lion)","ncbi_taxon_id":9689,"taxonomy":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Laurasiatheria","Carnivora","Feliformia","Felidae","Pantherinae","Panthera"],"sequence":"MEIKDQGAQMEPLLPTRNDEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDIRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKGLGGQQKGHTSPCGMKQRHEKGPPHQQEREVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHGGHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNDTLKEWRESNISASDIIWENLTVSECKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQSMLAMEDEGTVQLPLEGHYRDDPSVINISDEMSKTALWRNLLMTADNSKDKESSFPSKSSPS","localization":["Basolateral cell membrane; Multi-pass membrane protein","Cell membrane; Multi-pass membrane protein","Lateral cell membrane; Multi-pass membrane protein","Membrane; Multi- pass membrane protein"],"uniref100":"UniRef100_A0A8C8XRM6","uniref90":"UniRef90_Q6U841","uniref50":"UniRef50_Q2Y0W8","uniparc":"UPI000F2FE950","prediction-transmembrane-uniprot":{"regions":[[510,532],[597,620],[627,645],[725,743],[763,781],[811,830],[851,875],[911,933],[1006,1023]],"content_count":190,"content_fraction":0.16994633273703041},"homology-domain-gene3d":{"regions":[[112,457]],"content_fraction":0.309,"content_count":346,"regions_ids":["3.40.930.10"],"regions_names":["Phosphotransferase/anion transporter"]},"homology-domain-pfam":{"regions":[[115,434],[481,1040]],"content_fraction":0.787,"content_count":880,"regions_ids":["PF07565","PF00955"],"regions_names":["Band 3 cytoplasmic domain","Bicarbonate transporter-like, transmembrane domain"]},"homology-domain-merge":{"regions":[[112,457],[481,1040]],"content_fraction":0.81,"content_count":906},"prediction-disorder-disHL":{"regions":[[1,26],[30,30],[36,46],[51,98],[106,112],[144,154],[221,234],[245,259],[261,265],[270,277],[282,295],[297,301],[304,312],[362,363],[409,413],[427,450],[465,476],[743,756],[782,788],[843,845],[892,903],[1031,1043],[1057,1059],[1069,1082],[1100,1118]],"content_count":302,"content_fraction":0.27},"prediction-disorder-dis465":{"regions":[[1,8],[21,24],[58,95],[132,133],[147,150],[218,227],[248,267],[269,269],[273,277],[288,314],[443,450],[459,472],[893,898],[1044,1058],[1104,1118]],"content_count":177,"content_fraction":0.158},"prediction-disorder-espD":{"regions":[[1066,1118]],"content_count":53,"content_fraction":0.047},"prediction-disorder-espN":{"regions":[[1,30],[43,46],[49,96],[103,114],[128,132],[145,153],[198,318],[325,331],[376,383],[426,482],[653,656],[672,678],[713,721],[782,785],[796,798],[1038,1080],[1100,1118]],"content_count":390,"content_fraction":0.349},"prediction-disorder-espX":{"regions":[[1,22],[51,97],[248,249],[279,280],[285,303],[440,476],[1040,1056],[1098,1118]],"content_count":167,"content_fraction":0.149},"prediction-disorder-glo":{"regions":[[4,4],[6,6],[59,63],[80,94],[245,259],[280,309],[427,444],[446,449],[454,454],[457,478],[561,567],[668,680],[712,721],[785,793],[795,808],[895,899],[1071,1080],[1104,1109],[1111,1112],[1114,1118]],"content_count":193,"content_fraction":0.173},"prediction-disorder-iupl":{"regions":[[1,37],[53,53],[59,106],[112,114],[192,193],[196,197],[199,199],[203,231],[238,276],[278,323],[386,387],[437,474],[1045,1059],[1061,1061],[1105,1118]],"content_count":278,"content_fraction":0.249},"prediction-disorder-iups":{"regions":[[1,23],[25,27],[53,116],[207,207],[211,233],[240,324],[432,477],[681,681],[1046,1074],[1082,1082],[1105,1118]],"content_count":290,"content_fraction":0.259},"prediction-low_complexity-seg":{"regions":[[57,79],[1041,1055],[1104,1118]],"content_count":53,"content_fraction":0.047},"prediction-lip-anchor":{"regions":[[1,13],[27,38],[44,57],[97,103],[118,121],[164,178],[217,217],[230,244],[255,272],[280,291],[297,301],[319,323],[420,421],[514,515],[1090,1100]],"content_count":136,"content_fraction":0.122},"prediction-disorder-th_50":{"regions":[[1,26],[53,97],[106,106],[112,112],[218,231],[245,267],[269,277],[279,314],[432,476],[1045,1059],[1069,1080],[1100,1118]],"content_count":246,"content_fraction":0.22},"prediction-disorder-mobidb_lite":{"regions":[[1,23],[58,96],[245,312],[457,476]],"content_count":150,"content_fraction":0.134,"scores":[0.75,0.75,0.75,0.875,0.75,0.875,0.75,0.75,0.625,0.625,0.625,0.625,0.625,0.625,0.625,0.625,0.625,0.625,0.625,0.625,0.75,0.75,0.625,0.5,0.5,0.5,0.375,0.25,0.25,0.375,0.125,0.125,0.125,0.125,0.125,0.25,0.25,0.125,0.125,0.125,0.125,0.125,0.25,0.25,0.25,0.25,0,0,0.125,0.125,0.375,0.375,0.625,0.5,0.5,0.5,0.5,0.625,0.875,0.875,0.875,0.875,0.875,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.875,0.875,0.875,0.875,0.875,0.875,0.875,0.875,0.875,0.875,0.875,0.875,0.875,0.875,0.875,0.75,0.625,0.5,0.375,0.25,0.25,0.25,0.25,0.375,0.375,0.375,0.5,0.375,0.375,0.375,0.375,0.375,0.5,0.375,0.375,0.125,0.125,0,0,0,0,0,0,0,0,0,0,0,0.125,0.125,0.125,0.125,0.25,0.125,0,0,0,0,0,0,0,0,0,0,0.125,0.25,0.25,0.375,0.375,0.375,0.375,0.25,0.25,0.25,0.125,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.125,0.125,0,0,0.125,0.125,0.125,0.25,0.125,0.125,0.125,0.25,0.25,0.25,0.25,0.375,0.25,0.25,0.25,0.375,0.375,0.375,0.375,0.375,0.375,0.375,0.5,0.5,0.5,0.625,0.625,0.625,0.625,0.625,0.625,0.625,0.5,0.5,0.5,0.5,0.375,0.375,0.25,0.125,0.125,0.125,0.25,0.25,0.375,0.375,0.375,0.375,0.375,0.625,0.625,0.625,0.875,0.875,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.5,0.625,0.625,0.625,0.625,0.625,0.5,0.5,0.375,0.5,0.5,0.5,0.5,0.625,0.625,0.625,0.625,0.5,0.375,0.5,0.625,0.5,0.625,0.625,0.625,0.75,0.75,0.75,0.875,0.875,0.875,0.875,0.875,0.875,0.875,0.875,0.75,0.875,0.875,0.875,0.875,0.875,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.75,0.625,0.625,0.625,0.5,0.5,0.375,0.375,0.375,0.375,0.25,0.25,0.25,0.25,0.25,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.125,0.125,0,0,0,0,0,0,0,0,0,0,0,0,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0,0,0.125,0.125,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.125,0.125,0.125,0.125,0.125,0,0,0,0,0,0,0,0,0,0,0,0,0.125,0.375,0.375,0.375,0.375,0.375,0.5,0.5,0.5,0.5,0.5,0.625,0.625,0.625,0.75,0.75,0.75,0.875,0.875,0.75,0.875,0.875,0.875,0.875,0.75,0.5,0.5,0.5,0.625,0.5,0.5,0.625,0.625,0.75,0.75,0.75,0.75,0.75,0.75,0.875,0.875,0.875,0.875,0.875,0.875,0.875,0.875,0.75,0.75,0.625,0.625,0.375,0.25,0.125,0.125,0.125,0.125,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.125,0.125,0.125,0.125,0,0,0,0,0,0,0,0,0,0,0,0.125,0.125,0.125,0.125,0.25,0.25,0.25,0.25,0.25,0.25,0.25,0.125,0.125,0.125,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.125,0.25,0.25,0.25,0.25,0.25,0.25,0.25,0.25,0.25,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.25,0.25,0.25,0.375,0.25,0.25,0.25,0.125,0.125,0.125,0.125,0.125,0,0.125,0.25,0.25,0.25,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.125,0.125,0.125,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.125,0.25,0.25,0.375,0.375,0.375,0.375,0.25,0.125,0.125,0.125,0.125,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.25,0.25,0.375,0.375,0.375,0.375,0.375,0.5,0.625,0.625,0.625,0.625,0.625,0.625,0.625,0.625,0.625,0.625,0.625,0.625,0.625,0.5,0.25,0.375,0.25,0.25,0.25,0.25,0.375,0.375,0.375,0.5,0.5,0.625,0.625,0.625,0.625,0.5,0.5,0.5,0.5,0.5,0.5,0.25,0.375,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.125,0.25,0.25,0.5,0.5,0.5,0.5,0.75,1,1,1,1,1,0.875,1,1,0.875,1,1,1,1,1]},"prediction-positive_polyelectrolyte-mobidb_lite_sub":{"regions":[[59,76]],"content_count":18,"content_fraction":0.016},"prediction-polyampholyte-mobidb_lite_sub":{"regions":[[77,90]],"content_count":14,"content_fraction":0.013},"prediction-polar-mobidb_lite_sub":{"regions":[[248,264]],"content_count":17,"content_fraction":0.015},"prediction-extended-mobidb_lite_sub":{"regions":[[245,312]],"content_count":69,"content_fraction":0.062,"regions_params":[0.559]}}